Jump to main content
Jump to site search

Issue 42, 2015
Previous Article Next Article

Generation of cycloheptynes and cyclooctynes via a sulfoxide–magnesium exchange reaction of readily synthesized 2-sulfinylcycloalkenyl triflates

Author affiliations

Abstract

Cycloheptynes and cyclooctynes were efficiently generated via a sulfoxide–magnesium exchange reaction of readily synthesized 2-sulfinylcycloalkenyl triflates. Cycloadditions between various ynophiles and the cycloalkynes generated by this method proceeded efficiently, providing an easy method to prepare a wide range of heterocycles fused with seven- or eight-membered carbocycles.

Graphical abstract: Generation of cycloheptynes and cyclooctynes via a sulfoxide–magnesium exchange reaction of readily synthesized 2-sulfinylcycloalkenyl triflates

Back to tab navigation

Supplementary files

Publication details

The article was received on 02 Mar 2015, accepted on 07 Apr 2015 and first published on 09 Apr 2015


Article type: Communication
DOI: 10.1039/C5CC01784J
Citation: Chem. Commun., 2015,51, 8745-8748
  •   Request permissions

    Generation of cycloheptynes and cyclooctynes via a sulfoxide–magnesium exchange reaction of readily synthesized 2-sulfinylcycloalkenyl triflates

    S. Yoshida, F. Karaki, K. Uchida and T. Hosoya, Chem. Commun., 2015, 51, 8745
    DOI: 10.1039/C5CC01784J

Search articles by author

Spotlight

Advertisements