Issue 33, 2015
From the journal:

Chemical Communications

Scaling up an electrochemical signal with a catalytic hairpin assembly coupling nanocatalyst label for DNA detection†

Xu Hun,*a   Guoliang Xiea  and  Xiliang Luo*a  

* Corresponding authors

a Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, Shandong Provincial Key Laboratory Of Biochemical Analysis, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China
E-mail: hunxu@sohu.com, xiliangluo@hotmail.com
Fax: +86-532-84023927
Tel: +86-532-84023927

Abstract

A strategy for the electrochemical detection of DNA based on catalytic hairpin assembly combined with nanocatalyst label-based redox cycling reaction signal amplification. A superior detection limit of 0.3 aM toward DNA can be achieved.

Graphical abstract: Scaling up an electrochemical signal with a catalytic hairpin assembly coupling nanocatalyst label for DNA detection

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Article information

DOI
https://doi.org/10.1039/C5CC00680E
Article type
Communication
Submitted
24 Jan 2015
Accepted
28 Jan 2015
First published
29 Jan 2015

Chem. Commun., 2015,51, 7100-7103

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Scaling up an electrochemical signal with a catalytic hairpin assembly coupling nanocatalyst label for DNA detection

X. Hun, G. Xie and X. Luo, Chem. Commun., 2015, 51, 7100 DOI: 10.1039/C5CC00680E

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