Issue 33, 2015
From the journal:

Chemical Communications

Combination drug release of smart cyclodextrin-gated mesoporous silica nanovehicles†

Shengwang Zhou,a   Huizi Sha,b   Xiaokang Ke,a   Baorui Liu,b   Xizhang Wanga  and  Xuezhong Du*a  

* Corresponding authors

a Key Laboratory of Mesoscopic Chemistry (Ministry of Education), State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China
E-mail: xzdu@nju.edu.cn

b The Comprehensive Cancer Center of Drum-Tower Hospital, Medical School of Nanjing University & Clinical Cancer Institute of Nanjing University, Nanjing 210008, China

Abstract

An integrated γ-cyclodextrin-gated mesoporous silica delivery system via dual dynamic covalent bonds was constructed with dual drug loading for simultaneous and cascade release in targeted combination drug therapy.

Graphical abstract: Combination drug release of smart cyclodextrin-gated mesoporous silica nanovehicles

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Article information

DOI
https://doi.org/10.1039/C5CC00585J
Article type
Communication
Submitted
21 Jan 2015
Accepted
19 Mar 2015
First published
19 Mar 2015

Chem. Commun., 2015,51, 7203-7206

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Combination drug release of smart cyclodextrin-gated mesoporous silica nanovehicles

S. Zhou, H. Sha, X. Ke, B. Liu, X. Wang and X. Du, Chem. Commun., 2015, 51, 7203 DOI: 10.1039/C5CC00585J

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