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Issue 29, 2015
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meso-Methylhydroxy BODIPY: a scaffold for photo-labile protecting groups

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Abstract

Here, we show that by installing a meso-methylhydroxy moiety, the boron dipyrromethene (BODIPY) scaffold can be converted into an efficient caging group, removable by green light. We describe caging and uncaging of important chemical functionalities and demonstrate green light mediated control over biological processes in cultured cell lines and neurons.

Graphical abstract: meso-Methylhydroxy BODIPY: a scaffold for photo-labile protecting groups

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Supplementary files

Article information


Submitted
20 Jan 2015
Accepted
27 Feb 2015
First published
03 Mar 2015

Chem. Commun., 2015,51, 6369-6372
Article type
Communication
Author version available

meso-Methylhydroxy BODIPY: a scaffold for photo-labile protecting groups

N. Rubinstein, P. Liu, E. W. Miller and R. Weinstain, Chem. Commun., 2015, 51, 6369
DOI: 10.1039/C5CC00550G

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