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Issue 21, 2015
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A multiple gadolinium complex decorated fullerene as a highly sensitive T1 contrast agent

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Abstract

We report a simple strategy to construct a multiple gadolinium complex decorated fullerene (CGDn) as an enhanced T1 contrast agent. The CGDn exhibits much higher T1 relaxivity (∼49.7 mM−1 s−1) than individual Gd-DOTA, and shows excellent T1 contrast enhancement ability both in vitro and in vivo.

Graphical abstract: A multiple gadolinium complex decorated fullerene as a highly sensitive T1 contrast agent

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Publication details

The article was received on 12 Jan 2015, accepted on 03 Feb 2015 and first published on 03 Feb 2015


Article type: Communication
DOI: 10.1039/C5CC00285K
Citation: Chem. Commun., 2015,51, 4390-4393
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    A multiple gadolinium complex decorated fullerene as a highly sensitive T1 contrast agent

    L. Wang, X. Zhu, X. Tang, C. Wu, Z. Zhou, C. Sun, S. Deng, H. Ai and J. Gao, Chem. Commun., 2015, 51, 4390
    DOI: 10.1039/C5CC00285K

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