Issue 28, 2015

A ratiometric fluorescent molecular probe for visualization of mitochondrial temperature in living cells

Abstract

Mitochondrial thermodynamics is the key to understand cellular activities related to homeostasis and energy balance. Here, we report the first ratiometric fluorescent molecular probe (Mito-RTP) that is selectively localized in the mitochondria and visualize the temperature. We confirmed that Mito-RTP could work as a ratiometric thermometer in a cuvette and living cells.

Graphical abstract: A ratiometric fluorescent molecular probe for visualization of mitochondrial temperature in living cells

Supplementary files

Article information

Article type
Communication
Submitted
27 Dec 2014
Accepted
26 Feb 2015
First published
26 Feb 2015

Chem. Commun., 2015,51, 6194-6197

Author version available

A ratiometric fluorescent molecular probe for visualization of mitochondrial temperature in living cells

M. Homma, Y. Takei, A. Murata, T. Inoue and S. Takeoka, Chem. Commun., 2015, 51, 6194 DOI: 10.1039/C4CC10349A

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