Issue 22, 2015

A non-aggregated and tumour-associated macrophage-targeted photosensitiser for photodynamic therapy: a novel zinc(ii) phthalocyanine containing octa-sulphonates

Abstract

A novel zinc(II) phthalocyanine bearing octa-sulphonates has been prepared, which is non-aggregated in water, highly photoactive and low dark-toxic. More interestingly, it exhibits specific affinity to macrophages via the scavenger receptor-A, and can selectively accumulate in tumour sites.

Graphical abstract: A non-aggregated and tumour-associated macrophage-targeted photosensitiser for photodynamic therapy: a novel zinc(ii) phthalocyanine containing octa-sulphonates

Supplementary files

Article information

Article type
Communication
Submitted
12 Dec 2014
Accepted
10 Feb 2015
First published
11 Feb 2015

Chem. Commun., 2015,51, 4704-4707

A non-aggregated and tumour-associated macrophage-targeted photosensitiser for photodynamic therapy: a novel zinc(II) phthalocyanine containing octa-sulphonates

X. Li, M. Ke, M. Zhang, Q. Tang, B. Zheng and J. Huang, Chem. Commun., 2015, 51, 4704 DOI: 10.1039/C4CC09934F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements