Issue 11, 2015
From the journal:

Chemical Communications

Monitoring the cytosolic entry of cell-penetrating peptides using a pH-sensitive fluorophore†

Ziqing Qian,a   Patrick G. Doughertya  and  Dehua Pei*a  

* Corresponding authors

a Department of Chemistry and Biochemistry, The Ohio State University, 484 West 12th Avenue, Columbus, OH 43210, USA
E-mail: pei.3@osu.edu

Abstract

We report a simple, effective method to assess the cytosolic delivery efficiency and kinetics of cell-penetrating peptides using a pH-sensitive fluorescent probe, naphthofluorescein.

Graphical abstract: Monitoring the cytosolic entry of cell-penetrating peptides using a pH-sensitive fluorophore

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Article information

DOI
https://doi.org/10.1039/C4CC09441G
Article type
Communication
Submitted
25 Nov 2014
Accepted
11 Dec 2014
First published
17 Dec 2014

Chem. Commun., 2015,51, 2162-2165

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Monitoring the cytosolic entry of cell-penetrating peptides using a pH-sensitive fluorophore

Z. Qian, P. G. Dougherty and D. Pei, Chem. Commun., 2015, 51, 2162 DOI: 10.1039/C4CC09441G

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