Complete discrimination of ephedrine and pseudoephedrine, both in solution and in the solid state, was achieved with a phosphonate cavitand receptor. The molecular origin of the epimer discrimination was revealed by the crystal structure of the respective complexes.
E. Biavardi, F. Ugozzoli and C. Massera, Chem. Commun., 2015, 51, 3426 DOI: 10.1039/C4CC09387A
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