Seema Dhiman and S. S. V. Ramasastry
Chem. Commun., 2015,51, 557-560
DOI:
10.1039/C4CC08174A,
Communication
An efficient relay catalytic process involving Au(I)/Brønsted acid to access various polysubstituted cyclopentannulated indoles from easily accessible 1-(2-aminophenyl)prop-2-ynols and readily available 1,3-dicarbonyls has been developed. In an unprecedented event, the intermediate 2-indolylmethyl cations undergo the cation-Ene reaction with various 1,3-dicarbonyls followed by an intramolecular Friedel–Crafts-type reaction generating functionalized cyclopenta[b]indoles.