Issue 1, 2015
From the journal:

Chemical Communications

Self-assembled levan nanoparticles for targeted breast cancer imaging†

Sun-Jung Kim,a   Pan Kee Baeb  and  Bong Hyun Chung*abc  

* Corresponding authors

a BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 305-806, Republic of Korea
E-mail: chungbh@kribb.re.kr
Fax: +82-42-879-8594
Tel: +82-42-860-4442

b BioNano Health Guard Research Center, 125 Gwahak-ro, Yuseong-gu, Daejeon 305-806, Republic of Korea

c Nanobiotechnology Major, School of Engineering, University of Science and Technology (UST), 125 Gwahak-ro, Yuseong-gu, Daejeon 305-806, Republic of Korea

Abstract

We report on the targeted imaging of breast cancer using self-assembled levan nanoparticles. Indocyanine green (ICG) was encapsulated in levan nanoparticles via self-assembly. Levan–ICG nanoparticles were found to be successfully accumulated in breast cancer via specific interaction between fructose moieties in levan and overexpressed glucose transporter 5 in breast cancer cells.

Graphical abstract: Self-assembled levan nanoparticles for targeted breast cancer imaging

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C4CC07679F
Article type
Communication
Submitted
29 Sep 2014
Accepted
27 Oct 2014
First published
10 Nov 2014

Chem. Commun., 2015,51, 107-110

Permissions

Request permissions

Self-assembled levan nanoparticles for targeted breast cancer imaging

S. Kim, P. K. Bae and B. H. Chung, Chem. Commun., 2015, 51, 107 DOI: 10.1039/C4CC07679F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements