Issue 11, 2015
From the journal:

Chemical Communications

A photoCORM nanocarrier for CO release using NIR light†

Agustin E. Pierri,ab   Po-Ju Huang,a   John V. Garcia,a   James G. Stanfill,a   Megan Chui,a   Guang Wu,a   Nanfeng Zheng*b  and  Peter C. Ford*a  

* Corresponding authors

a Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA, USA
E-mail: ford@chem.ucsb.edu

b State Key Laboratory for Physical Chemistry of Solid Surfaces and Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China
E-mail: nfzheng@xmu.edu.cn

Abstract

A water-soluble nanocarrier for a photo-activated CO releasing moiety (photoCORM) that can be triggered with NIR excitation is described. This has an upconversion nanoparticle core encapsulated by an amphiphilic polymer imparting both water solubility and a hydrophobic interior containing the photoCORM trans-Mn(bpy)(PPh3)2(CO)2. Such an ensemble offers a unique strategy for CO delivery to biological targets.

Graphical abstract: A photoCORM nanocarrier for CO release using NIR light

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Article information

DOI
https://doi.org/10.1039/C4CC06766E
Article type
Communication
Submitted
27 Aug 2014
Accepted
16 Dec 2014
First published
16 Dec 2014

Chem. Commun., 2015,51, 2072-2075

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A photoCORM nanocarrier for CO release using NIR light

A. E. Pierri, P. Huang, J. V. Garcia, J. G. Stanfill, M. Chui, G. Wu, N. Zheng and P. C. Ford, Chem. Commun., 2015, 51, 2072 DOI: 10.1039/C4CC06766E

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