A long-wavelength fluorescent turn-on probe for video detection of biological thiols in living cells†
Abstract
We have designed and synthesized the compound FR-thiol based on a new far-red platform as a turn-on fluorescent probe for biological thiols. The turn-on probe FR-thiol displayed a high selectivity and sensitivity to thiols. Finally, we have demonstrated that FR-thiol is suitable for video observation of biological thiols in living cells.