Jump to main content
Jump to site search

Issue 9, 2015
Previous Article Next Article

Developing a nanostructure electrochemical sensor for simultaneous determination of cysteine and tryptophan

Author affiliations

Abstract

A modified carbon paste electrode (CPE) was prepared based on a newly synthesized compound 14-(4-hydroxyphenyl)-14-H-dibenzo[a,j]-xanthene (HDX) and multi-wall carbon nanotubes (MWCNTs). At first, the redox properties of the modified electrode were studied by cyclic voltammetry (CV). Then, the modified electrode was used as an electrochemical sensor for the oxidation of cysteine (Cys). Under the optimum pH of 8.5, the overpotential of Cys oxidation decreased about 280 mV at the modified electrode rather than at the unmodified CPE. The differential pulse voltammetry (DPV) curve of Cys at the electrochemical sensor exhibited two linear dynamic ranges with a detection limit (3sb) of 1.0 μM. Also, DPV was used for the simultaneous determination of Cys and tryptophan (Try) using the electrochemical sensor. The proposed electrochemical sensor was used for the determination of these substances in real samples (i.e. tablets and human serums).

Graphical abstract: Developing a nanostructure electrochemical sensor for simultaneous determination of cysteine and tryptophan

Back to tab navigation

Publication details

The article was received on 18 Mar 2015, accepted on 21 Mar 2015 and first published on 23 Mar 2015


Article type: Paper
DOI: 10.1039/C5AY00727E
Author version
available:
Download author version (PDF)
Anal. Methods, 2015,7, 3920-3928

  •   Request permissions

    Developing a nanostructure electrochemical sensor for simultaneous determination of cysteine and tryptophan

    A. Benvidi, M. M. Ansaripour, N. Rajabzadeh, H. R. Zare and B. F. Mirjalili, Anal. Methods, 2015, 7, 3920
    DOI: 10.1039/C5AY00727E

Search articles by author

Spotlight

Advertisements