A novel nonenzymatic glucose sensor based on magnetic copper ferrite immobilized on multiwalled carbon nanotubes

Abstract

A novel nonenzymatic glucose sensor was constructed based on the magnetic loading of copper ferrite (CuFe₂O₄)–multiwalled carbon nanotubes (MWCNTs) composites without using an additive polymer binder. The CuFe₂O₄–MWCNTs composites were synthesized via a hydrothermal method and characterized by transmission electron microscopy (TEM), X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The modified electrode was characterized by electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV) and chronoamperometry. The proposed sensor exhibited rapid response time (less than 5 s), a wide linear range of 0.5–1400 μM (R² = 0.996) and a low detection limit of 0.2 μM (S/N = 3) towards glucose oxidation. Furthermore, the sensor was successfully applied to determine glucose in human serum samples with good accuracy and high precision. These results indicated that the sensor could be used as a promising platform for the determination of glucose.