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Issue 6, 2015
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A paper based microfluidic device for easy detection of uric acid using positively charged gold nanoparticles

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Abstract

A paper based microfluidic device is fabricated that can rapidly detect very low concentrations of uric acid (UA) using 3,5,3′,5′-tetramethyl benzidine (TMB), H2O2 and positively charged gold nanoparticles ((+)AuNPs). In the presence of (+)AuNPs, H2O2 reacts with TMB to produce a bluish-green colour which becomes colourless on reaction with UA. This colorimetric method can detect as low as 8.1 ppm of UA within <20 minutes on white filter paper. This technique provides an alternative way for UA detection.

Graphical abstract: A paper based microfluidic device for easy detection of uric acid using positively charged gold nanoparticles

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Article information


Submitted
18 Dec 2014
Accepted
20 Jan 2015
First published
21 Jan 2015

Analyst, 2015,140, 1817-1821
Article type
Communication
Author version available

A paper based microfluidic device for easy detection of uric acid using positively charged gold nanoparticles

A. Kumar, A. Hens, R. K. Arun, M. Chatterjee, K. Mahato, K. Layek and N. Chanda, Analyst, 2015, 140, 1817
DOI: 10.1039/C4AN02333A

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