Issue 13, 2015

Blood, sweat, and tears: developing clinically relevant protein biosensors for integrated body fluid analysis

Abstract

Biosensors are being developed to provide rapid, quantitative, diagnostic information to clinicians in order to help guide patient treatment, without the need for centralised laboratory assays. The success of glucose monitoring is a key example of where technology innovation has met a clinical need at multiple levels – from the pathology laboratory all the way to the patient's home. However, few other biosensor devices are currently in routine use. Here we review the challenges and opportunities regarding the integration of biosensor techniques into body fluid sampling approaches, with emphasis on the point-of-care setting.

Graphical abstract: Blood, sweat, and tears: developing clinically relevant protein biosensors for integrated body fluid analysis

Article information

Article type
Critical Review
Submitted
09 Mar 2015
Accepted
08 Apr 2015
First published
09 Apr 2015

Analyst, 2015,140, 4350-4364

Author version available

Blood, sweat, and tears: developing clinically relevant protein biosensors for integrated body fluid analysis

S. R. Corrie, J. W. Coffey, J. Islam, K. A. Markey and M. A. F. Kendall, Analyst, 2015, 140, 4350 DOI: 10.1039/C5AN00464K

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