Jump to main content
Jump to site search

Issue 6, 2014
Previous Article Next Article

Preparation of core–shell Fe3O4@poly(dopamine) magnetic nanoparticles for biosensor construction

Author affiliations

Abstract

Novel core–shell Fe3O4@poly(dopamine) magnetic nanoparticles were prepared through an in situ self-polymerization method. The hybrid nanomaterial showed an average core diameter of 11 ± 3 nm and a polymer thin film thickness of 1.8 ± 0.2 nm. The core–shell nanoparticles were employed as solid supports for the covalent immobilization of horseradish peroxidase (HRP), and the resulting biofunctionalized magnetic nanoparticles were employed to construct an amperometric biosensor for H2O2. The enzyme biosensor showed a high sensitivity of 442.14 mA M−1 cm−2, a low limit of detection of 182 nM, a wide linear range from 6.0 × 10−7 to 8.0 × 10−4 M and high stability for 1 month.

Graphical abstract: Preparation of core–shell Fe3O4@poly(dopamine) magnetic nanoparticles for biosensor construction

Back to tab navigation

Supplementary files

Publication details

The article was received on 21 Aug 2013, accepted on 21 Nov 2013 and first published on 25 Nov 2013


Article type: Paper
DOI: 10.1039/C3TB21171A
J. Mater. Chem. B, 2014,2, 739-746

  •   Request permissions

    Preparation of core–shell Fe3O4@poly(dopamine) magnetic nanoparticles for biosensor construction

    M. Martín, P. Salazar, R. Villalonga, S. Campuzano, J. M. Pingarrón and J. L. González-Mora, J. Mater. Chem. B, 2014, 2, 739
    DOI: 10.1039/C3TB21171A

Search articles by author

Spotlight

Advertisements