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Issue 42, 2014
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Molecular recognition of nucleic acids by nucleolipid/dendrimer surface complexes

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Abstract

We show for the first time that 1,2-dilauroyl-sn-glycero-3-phosphatidyladenosine nucleolipid surface complexes with cationic poly(amidoamine) dendrimers can be used to selectively bind DNA including oligonucleotides. This molecular recognition has high potential for applications involving biomedical and bioanalytic devices as well as drug delivery systems based on nucleic acids.

Graphical abstract: Molecular recognition of nucleic acids by nucleolipid/dendrimer surface complexes

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Publication details

The article was received on 05 Aug 2014, accepted on 05 Sep 2014 and first published on 05 Sep 2014


Article type: Communication
DOI: 10.1039/C4SM01733A
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Citation: Soft Matter, 2014,10, 8401-8405
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    Molecular recognition of nucleic acids by nucleolipid/dendrimer surface complexes

    M. Y. Arteta, D. Berti, C. Montis, R. A. Campbell, L. A. Clifton, M. W. A. Skoda, O. Soltwedel, P. Baglioni and T. Nylander, Soft Matter, 2014, 10, 8401
    DOI: 10.1039/C4SM01733A

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