Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 32, 2014
Previous Article Next Article

Statistical analysis of vesicle morphology dynamics based on a free energy landscape

Author affiliations

Abstract

We here present a method to reconstruct effective free energy landscapes (FELs) of lipid vesicles from the statistical analysis of a large number of microscope images. This method, not only allows us to define possible energy landscapes, but also highlights minority vesicle shapes that were otherwise hidden in the majority. When compared with temporal evolution of deforming lipid vesicles, it was found that the trajectory of deforming vesicles was in accordance with the reconstructed landscape, in which the minority shapes play a key role. When compared with theoretical models, it revealed that the vesicle shapes characterised in the reconstructed FELs were consistent with the theoretically predicted shapes. These results suggest that the FEL analysis can be a useful tool to investigate the morphological dynamics of lipid vesicles, in conjunction with other analytical methods.

Graphical abstract: Statistical analysis of vesicle morphology dynamics based on a free energy landscape

Back to tab navigation

Supplementary files

Article information


Submitted
07 May 2014
Accepted
29 May 2014
First published
29 May 2014

Soft Matter, 2014,10, 6038-6046
Article type
Paper
Author version available

Statistical analysis of vesicle morphology dynamics based on a free energy landscape

S. Tsuda, H. Suzuki and T. Yomo, Soft Matter, 2014, 10, 6038
DOI: 10.1039/C4SM00992D

Social activity

Search articles by author

Spotlight

Advertisements