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Issue 106, 2014
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Dendritic polyglycerol cyclodextrin amphiphiles and their self-assembled architectures to transport hydrophobic guest molecules

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Abstract

Here we report for the first time a microwave assisted synthesis of polyglycerol dendron functionalized cyclodextrins (CD) with hydrophobic tails. These amphiphilic CDs consist of seven polyglycerol dendrons and fourteen alkyl chains on the primary and secondary rims of the cyclodextrin core, respectively. They self-assemble to form nanostructures in aqueous solutions and efficiently encapsulate hydrophobic aromatic guests. The size and shape of the self-assemblies and also their ability to encapsulate guest molecules depend on the generation of conjugated polyglycerol dendrons.

Graphical abstract: Dendritic polyglycerol cyclodextrin amphiphiles and their self-assembled architectures to transport hydrophobic guest molecules

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Supplementary files

Article information


Submitted
01 Oct 2014
Accepted
06 Nov 2014
First published
07 Nov 2014

This article is Open Access

RSC Adv., 2014,4, 61656-61659
Article type
Communication
Author version available

Dendritic polyglycerol cyclodextrin amphiphiles and their self-assembled architectures to transport hydrophobic guest molecules

A. C. Rodrigo‡, S. Malhotra‡, C. Böttcher, M. Adeli and R. Haag, RSC Adv., 2014, 4, 61656
DOI: 10.1039/C4RA11601A

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