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Issue 43, 2014
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An efficient multichannel probe to detect anions in different media and its real application in human blood plasma

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Abstract

A simple coumarin derived chromo and fluorogenic chemosensor has been synthesized and tested to detect anions in different medium. The designed chemosensor has shown a high colorimetric response for F and AcO ions in acetonitrile in which the color of solution changed from a yellow-green to red and orange respectively whereas, in aqueous medium the probe showed high fluorogenic response and selectively reacted with cyanide through a Michael type nucleophilic addition reaction in which a nonfluorescent (switched-off) color of the solution, “turn-on” to became fluorescent blue (switched-on). The multichannel mode of interaction between the probe and anions has been confirmed by absorption, emission, FT-IR, NMR, ESI-MS spectral data analysis. Moreover, the probe has shown high sensitivity to detect cyanide in a real sample, human blood plasma as well as on paper strips.

Graphical abstract: An efficient multichannel probe to detect anions in different media and its real application in human blood plasma

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Publication details

The article was received on 18 Mar 2014, accepted on 08 May 2014 and first published on 08 May 2014


Article type: Communication
DOI: 10.1039/C4RA02388A
Citation: RSC Adv., 2014,4, 22308-22317
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    An efficient multichannel probe to detect anions in different media and its real application in human blood plasma

    S. S. Razi, R. Ali, P. Srivastava, M. Shahid and A. Misra, RSC Adv., 2014, 4, 22308
    DOI: 10.1039/C4RA02388A

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