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Issue 38, 2014
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ZrCl4-promoted facile synthesis of indole derivatives

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Abstract

Zirconium(IV) chloride effectively activates nitrogen (N2) extrusion from aryl azidoacrylates followed by annulation to provide the desired indole products in moderate to good yields. The reaction proceeds at low temperature and in short reaction time and is applicable to a variety of substrates.

Graphical abstract: ZrCl4-promoted facile synthesis of indole derivatives

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Supplementary files

Article information


Submitted
12 Mar 2014
Accepted
17 Apr 2014
First published
18 Apr 2014

RSC Adv., 2014,4, 20048-20052
Article type
Communication
Author version available

ZrCl4-promoted facile synthesis of indole derivatives

J. Tummatorn, M. P. Gleeson, S. Krajangsri, C. Thongsornkleeb and S. Ruchirawat, RSC Adv., 2014, 4, 20048
DOI: 10.1039/C4RA02158D

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