A microfluidic chip based method utilized for effective screening of high-throughput peptide libraries was achieved. Continuous flow bead trapping, sorting, arraying and in situ sequencing was integrated. Peptide library screening with 105 beads was processed within 4 hours and peptide ligands toward the target protein AHA and APN were successfully discovered.
W. Wang, Z. Wei, Z. Wang, H. Ma, X. Bu and Z. Hu, RSC Adv., 2014, 4, 61767 DOI: 10.1039/C4RA12911C
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