Issue 102, 2014
From the journal:

RSC Advances

A benzimidazolium-based new flexible cleft built on the piperazine unit: a case of selective fluorometric sensing of ATP†

Kumaresh Ghosh,*a   Debojyoti Tarafdar,a   Asmita Samadderb  and  Anisur Rahman Khuda-Bukhshb  

* Corresponding authors

a Department of Chemistry, University of Kalyani, Kalyani-741235, India
E-mail: ghosh_k2003@yahoo.co.in
Fax: +91-3325828282
Tel: +91-3325828750

b Department of Zoology, University of Kalyani, Kalyani-741235, India

Abstract

A benzimidazole-based compound 1 built on the piperazine motif has been designed and synthesized. The chemosensor 1 is highly selective and sensitive towards ATP over ADP and AMP in CH3CN/H2O (1 : 1, v/v, using 10 mM HEPES buffer, pH 6.4) as evidenced by the significant change in emission. Furthermore, sensor 1 is cell permeable and can detect the presence of ATP in Human cervical cancer cells (HeLa).

Graphical abstract: A benzimidazolium-based new flexible cleft built on the piperazine unit: a case of selective fluorometric sensing of ATP

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C4RA11683F
Article type
Paper
Submitted
02 Oct 2014
Accepted
29 Oct 2014
First published
30 Oct 2014

RSC Adv., 2014,4, 58530-58535

Author version available

Download author version (PDF)

Permissions

Request permissions

A benzimidazolium-based new flexible cleft built on the piperazine unit: a case of selective fluorometric sensing of ATP

K. Ghosh, D. Tarafdar, A. Samadder and A. R. Khuda-Bukhsh, RSC Adv., 2014, 4, 58530 DOI: 10.1039/C4RA11683F

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements