A G-quadruplex-based platform for the detection of Hg2+ ions using a luminescent iridium(III) complex

Sheng Lin; Bingyong He; Daniel Shiu-Hin Chan; Philip Wai Hong Chan; Chung-Hang Leung; Dik-Lung Ma

doi:10.1039/C4RA11240G

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A G-quadruplex-based platform for the detection of Hg²⁺ ions using a luminescent iridium(iii) complex†

Sheng Lin,^a Bingyong He,^a Daniel Shiu-Hin Chan,^a Philip Wai Hong Chan,^bc Chung-Hang Leung^d and Dik-Lung Ma*^ae

Author affiliations

* Corresponding authors

^a Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
E-mail: edmondma@hkbu.edu.hk

^b School of Chemistry, Monash University, Clayton 3800, Victoria, Australia

^c Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore

^d State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China

^e Partner State Key Laboratory of Environmental and Biological Analysis, Hong Kong Baptist University, P. R. China

Abstract

We report herein the synthesis of a series of cyclometalated iridium(III) complexes as luminescent G-quadruplex-selective probes, which were used to construct an oligonucleotide-based platform for the dual detection and removal of Hg²⁺ ions.

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Article information

DOI: https://doi.org/10.1039/C4RA11240G
Article type: Communication
Submitted: 26 Sep 2014
Accepted: 20 Oct 2014
First published: 20 Oct 2014

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RSC Adv., 2014,4, 54826-54831

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A G-quadruplex-based platform for the detection of Hg²⁺ ions using a luminescent iridium(III) complex

S. Lin, B. He, D. Shiu-Hin Chan, P. W. Hong Chan, C. Leung and D. Ma, RSC Adv., 2014, 4, 54826 DOI: 10.1039/C4RA11240G

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