Issue 86, 2014
From the journal:

RSC Advances

Dendritic nanoconjugate containing optimum folic acid for targeted intracellular curcumin delivery†

Yunlan Fu,a   Xuli Gao,a   Ying Wan,b   Ju Zhang,c   Deling Kong,c   Zheng Wang*a  and  Yanjun Zhao*a  

* Corresponding authors

a Tianjin Key Laboratory for Modern Drug Delivery & High Efficiency, School of Pharmaceutical Science & Technology, Tianjin University, 92 Weijin Road, Tianjin 300072, China
E-mail: zhaoyj@tju.edu.cn, wangzheng2006@tju.edu.cn
Fax: +86-22-27404018
Tel: +86-22-27404018

b College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China

c Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China

Abstract

Based on surface-engineered poly(aminoamie) dendrimers, a novel type of targeted bifunctional nanoconjugate with optimum folic acid was designed to enhance the intracellular delivery of a highly pleiotropic active agent, curcumin.

Graphical abstract: Dendritic nanoconjugate containing optimum folic acid for targeted intracellular curcumin delivery

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Article information

DOI
https://doi.org/10.1039/C4RA08315F
Article type
Communication
Submitted
07 Aug 2014
Accepted
16 Sep 2014
First published
16 Sep 2014

RSC Adv., 2014,4, 46020-46023

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Dendritic nanoconjugate containing optimum folic acid for targeted intracellular curcumin delivery

Y. Fu, X. Gao, Y. Wan, J. Zhang, D. Kong, Z. Wang and Y. Zhao, RSC Adv., 2014, 4, 46020 DOI: 10.1039/C4RA08315F

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