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Issue 104, 2014
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Recent advances in the synthesis of 2-substituted benzothiazoles: a review

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Abstract

Benzothiazole can serve as unique and versatile scaffolds, especially in synthetic and pharmaceutical chemistry because of their potent and significant pharmacological activities. This important class of derivatives possess numerous pharmacological activities like antitumor, antimicrobial, anti-inflammatory, anticonvulsant, antidiabetic activities and so on. Many scientists have developed a wide range of methodologies for the synthesis of the 2-substituted benzothiazole nucleus and its derivatives using different types of catalysts to improve the selectivity, purity and yield of the products. Thus, the present review article focuses mainly on the different kind of reactions involved in synthesis of the 2-substituted benzothiazole nucleus and its derivatives.

Graphical abstract: Recent advances in the synthesis of 2-substituted benzothiazoles: a review

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Article information


Submitted
22 Jul 2014
Accepted
28 Oct 2014
First published
29 Oct 2014

RSC Adv., 2014,4, 60176-60208
Article type
Review Article
Author version available

Recent advances in the synthesis of 2-substituted benzothiazoles: a review

N. P. Prajapati, R. H. Vekariya, M. A. Borad and H. D. Patel, RSC Adv., 2014, 4, 60176
DOI: 10.1039/C4RA07437H

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