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Issue 104, 2014
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Recent advances in the synthesis of 2-substituted benzothiazoles: a review

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Abstract

Benzothiazole can serve as unique and versatile scaffolds, especially in synthetic and pharmaceutical chemistry because of their potent and significant pharmacological activities. This important class of derivatives possess numerous pharmacological activities like antitumor, antimicrobial, anti-inflammatory, anticonvulsant, antidiabetic activities and so on. Many scientists have developed a wide range of methodologies for the synthesis of the 2-substituted benzothiazole nucleus and its derivatives using different types of catalysts to improve the selectivity, purity and yield of the products. Thus, the present review article focuses mainly on the different kind of reactions involved in synthesis of the 2-substituted benzothiazole nucleus and its derivatives.

Graphical abstract: Recent advances in the synthesis of 2-substituted benzothiazoles: a review

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Publication details

The article was received on 22 Jul 2014, accepted on 28 Oct 2014 and first published on 29 Oct 2014


Article type: Review Article
DOI: 10.1039/C4RA07437H
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Citation: RSC Adv., 2014,4, 60176-60208
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    Recent advances in the synthesis of 2-substituted benzothiazoles: a review

    N. P. Prajapati, R. H. Vekariya, M. A. Borad and H. D. Patel, RSC Adv., 2014, 4, 60176
    DOI: 10.1039/C4RA07437H

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