Issue 77, 2014

Total syntheses of d-allo-1-deoxynojirimycin and l-talo-1-deoxynojirimycin via reductive cyclization

Abstract

Synthesis of a polyhydroxypiperidine framework for L-talo-1-deoxynojirimycin and D-allo-1-deoxynojirimycin was achieved from L-tartaric acid by employing flash dihydroxylation and reductive lactamisation as the key steps.

Graphical abstract: Total syntheses of d-allo-1-deoxynojirimycin and l-talo-1-deoxynojirimycin via reductive cyclization

Supplementary files

Article information

Article type
Paper
Submitted
09 Jul 2014
Accepted
19 Aug 2014
First published
21 Aug 2014

RSC Adv., 2014,4, 40852-40858

Total syntheses of D-allo-1-deoxynojirimycin and L-talo-1-deoxynojirimycin via reductive cyclization

S. P. Chavan, N. B. Dumare and K. P. Pawar, RSC Adv., 2014, 4, 40852 DOI: 10.1039/C4RA06884J

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