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Issue 81, 2014
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One step synthesis of maltose functionalized red fluorescent Ag cluster for specific glycoprotein detection and cellular imaging probe

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Abstract

The synthesis of non-cadmium based carbohydrate functionalized inorganic fluorescent nanoparticles has emerging potential applications in advanced biomedical science. Herein, we synthesized red fluorescent maltose functionalized silver clusters (AgC) using cysteamine modified maltose as a capping agent without adding any external reductant. The silver clusters had a hydrodynamic diameter of less than 5 nm with good colloidal, photochemical and fluorescent stability with a reasonably good fluorescence quantum yield. Maltose functionalized fluorescent silver clusters were produced in a one step procedure. Therefore, we exploited the maltose functionalized silver clusters for the visible detection of specific glycoprotein concanavalin-A. Because the synthesized red fluorescent maltose functionalized silver clusters possesses good photochemical stability and green light excitation, we used maltose functionalized red fluorescent AgC for HeLa cell labelling study.

Graphical abstract: One step synthesis of maltose functionalized red fluorescent Ag cluster for specific glycoprotein detection and cellular imaging probe

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Publication details

The article was received on 06 Jul 2014, accepted on 27 Aug 2014 and first published on 28 Aug 2014


Article type: Paper
DOI: 10.1039/C4RA06723A
RSC Adv., 2014,4, 43098-43104

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    One step synthesis of maltose functionalized red fluorescent Ag cluster for specific glycoprotein detection and cellular imaging probe

    S. Basiruddin and A. Chakraborty, RSC Adv., 2014, 4, 43098
    DOI: 10.1039/C4RA06723A

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