Issue 81, 2014

One step synthesis of maltose functionalized red fluorescent Ag cluster for specific glycoprotein detection and cellular imaging probe

Abstract

The synthesis of non-cadmium based carbohydrate functionalized inorganic fluorescent nanoparticles has emerging potential applications in advanced biomedical science. Herein, we synthesized red fluorescent maltose functionalized silver clusters (AgC) using cysteamine modified maltose as a capping agent without adding any external reductant. The silver clusters had a hydrodynamic diameter of less than 5 nm with good colloidal, photochemical and fluorescent stability with a reasonably good fluorescence quantum yield. Maltose functionalized fluorescent silver clusters were produced in a one step procedure. Therefore, we exploited the maltose functionalized silver clusters for the visible detection of specific glycoprotein concanavalin-A. Because the synthesized red fluorescent maltose functionalized silver clusters possesses good photochemical stability and green light excitation, we used maltose functionalized red fluorescent AgC for HeLa cell labelling study.

Graphical abstract: One step synthesis of maltose functionalized red fluorescent Ag cluster for specific glycoprotein detection and cellular imaging probe

Supplementary files

Article information

Article type
Paper
Submitted
06 Jul 2014
Accepted
27 Aug 2014
First published
28 Aug 2014

RSC Adv., 2014,4, 43098-43104

One step synthesis of maltose functionalized red fluorescent Ag cluster for specific glycoprotein detection and cellular imaging probe

S. Basiruddin and A. Chakraborty, RSC Adv., 2014, 4, 43098 DOI: 10.1039/C4RA06723A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements