Issue 71, 2014

Iron/acetic acid mediated intermolecular tandem C–C and C–N bond formation: an easy access to acridinone and quinoline derivatives

Abstract

An efficient iron/acetic acid mediated one pot reductive cyclization protocol was successfully developed for the synthesis of acridinone and quinoline derivatives. This highly efficient process proceeds under mild conditions, tolerates different functional groups, and provides various substituted acridinone and quinoline derivatives in good to excellent yields. In addition, biologically active compounds also accessed from this method.

Graphical abstract: Iron/acetic acid mediated intermolecular tandem C–C and C–N bond formation: an easy access to acridinone and quinoline derivatives

Supplementary files

Article information

Article type
Paper
Submitted
22 May 2014
Accepted
29 Jul 2014
First published
30 Jul 2014

RSC Adv., 2014,4, 37806-37811

Author version available

Iron/acetic acid mediated intermolecular tandem C–C and C–N bond formation: an easy access to acridinone and quinoline derivatives

R. R. Rajawinslin, S. D. Gawande, V. Kavala, Y. Huang, C. Kuo, T. Kuo, M. Chen, C. He and C. Yao, RSC Adv., 2014, 4, 37806 DOI: 10.1039/C4RA06410K

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