Issue 75, 2014
From the journal:

RSC Advances

Catalyst-free three-component reaction to synthesize chiral α-amino phosphine oxides†

Xi-An Li,a   Jia-Yuan Li,a   Bin Yanga  and  Shang-Dong Yang*ab  

* Corresponding authors

a State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. China
E-mail: yangshd@lzu.edu.cn

b State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Lanzhou, P. R. China
Fax: +86 9318912859
Tel: +86 9318912859

Abstract

A three-component reaction for high diastereoselective synthesis of chiral α-amino phosphine oxides has been developed and displayed environmentally friendly and atom efficient characteristics. The reaction proceeds smoothly without catalysts or additives.

Graphical abstract: Catalyst-free three-component reaction to synthesize chiral α-amino phosphine oxides

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Article information

DOI
https://doi.org/10.1039/C4RA05645K
Article type
Communication
Submitted
12 Jun 2014
Accepted
18 Aug 2014
First published
18 Aug 2014

RSC Adv., 2014,4, 39920-39923

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Catalyst-free three-component reaction to synthesize chiral α-amino phosphine oxides

X. Li, J. Li, B. Yang and S. Yang, RSC Adv., 2014, 4, 39920 DOI: 10.1039/C4RA05645K

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