Issue 64, 2014
From the journal:

RSC Advances

Winolides A–C, bioactive sesquiterpene lactones with unusual 5,6-secoeudesmane frameworks from Inula wissmanniana†

Xiang-Rong Cheng,‡ab   Wen-Hao Shao,‡c   Shou-De Zhang,‡a   Guo-Wei Wang,a   Lei Shan,c   Yun-Heng Shen,c   Qing-Yan Sun,*c   Hui-Zi Jina  and  Wei-Dong Zhang*ac  

* Corresponding authors

a School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, P. R. China
E-mail: wdzhangy@hotmail.com
Fax: +86-21-34205989
Tel: +86-21-34205989

b School of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu Province, P. R. China

c School of Pharmacy, Second Military Medical University, Shanghai 200433, P. R. China
E-mail: sqy_2000@163.com

Abstract

Winolides A–C (1–3), three bioactive sesquiterpene lactones with irregular 5,6-secoeudesmane frameworks, which probably arise from different dienol-benzene rearrangements, were isolated from Inula wissmanniana. Their structures and absolute configurations were established by extensive analysis of spectroscopic data, computational methods, and asymmetric synthesis.

Graphical abstract: Winolides A–C, bioactive sesquiterpene lactones with unusual 5,6-secoeudesmane frameworks from Inula wissmanniana

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Article information

DOI
https://doi.org/10.1039/C4RA05131A
Article type
Communication
Submitted
30 May 2014
Accepted
21 Jul 2014
First published
21 Jul 2014

RSC Adv., 2014,4, 33815-33818

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Winolides A–C, bioactive sesquiterpene lactones with unusual 5,6-secoeudesmane frameworks from Inula wissmanniana

X. Cheng, W. Shao, S. Zhang, G. Wang, L. Shan, Y. Shen, Q. Sun, H. Jin and W. Zhang, RSC Adv., 2014, 4, 33815 DOI: 10.1039/C4RA05131A

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