Issue 64, 2014
From the journal:

RSC Advances

Studies on the synthesis of a sugar triazole based ligand for protein and DNA binding†

Arasappan Hemamalinia  and  Thangamuthu Mohan Das*ab  

* Corresponding authors

a Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai-600 025, India
E-mail: tmdas_72@yahoo.com
Fax: +91-44-22352494
Tel: +91-44-22202814

b Department of Chemistry, School of Basic and Applied Sciences, Central University of Tamil Nadu, Thiruvarur-610 004, India
E-mail: tmohandas@cutn.ac.in
Fax: +91-4366-225312
Tel: +91-9489054264

Abstract

Bis-triazole derivatives accomplished by [3 + 2] cycloaddition methodology were well characterized. Interaction of bis-triazoles with BSA and CT-DNA had good correlation with experimental and docking studies. The compounds showed moderate to excellent antibacterial activity.

Graphical abstract: Studies on the synthesis of a sugar triazole based ligand for protein and DNA binding

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Article information

DOI
https://doi.org/10.1039/C4RA04084H
Article type
Paper
Submitted
04 May 2014
Accepted
24 Jul 2014
First published
29 Jul 2014

RSC Adv., 2014,4, 34189-34198

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Studies on the synthesis of a sugar triazole based ligand for protein and DNA binding

A. Hemamalini and T. M. Das, RSC Adv., 2014, 4, 34189 DOI: 10.1039/C4RA04084H

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