Jump to main content
Jump to site search

Issue 50, 2014
Previous Article Next Article

Manganese(ii) chloride catalyzed highly efficient one-pot synthesis of propargylamines and fused triazoles via three-component coupling reaction under solvent-free condition

Author affiliations

Abstract

A one-pot green and highly efficient method for the synthesis of propargylamines and diastereoselective synthesis of fused triazoles via three-component coupling in the presence of manganese(II) chloride as a catalyst and a catalyst-free 1,3-dipolar cycloaddition reaction, respectively, without using a co-catalyst or activator is reported. This methodology is efficient, eco-friendly, operationally simple and effective for reactions involving aromatic, aliphatic, and heterocyclic aldehydes, and provides an easy access to propargylamines in excellent yields, fused triazoles in good yield and excellent diastereoselectivities.

Graphical abstract: Manganese(ii) chloride catalyzed highly efficient one-pot synthesis of propargylamines and fused triazoles via three-component coupling reaction under solvent-free condition

Back to tab navigation

Supplementary files

Publication details

The article was received on 10 Apr 2014, accepted on 23 May 2014 and first published on 23 May 2014


Article type: Paper
DOI: 10.1039/C4RA03232B
Author version
available:
Download author version (PDF)
RSC Adv., 2014,4, 26301-26308

  •   Request permissions

    Manganese(II) chloride catalyzed highly efficient one-pot synthesis of propargylamines and fused triazoles via three-component coupling reaction under solvent-free condition

    S. N. Afraj, C. Chen and G. Lee, RSC Adv., 2014, 4, 26301
    DOI: 10.1039/C4RA03232B

Search articles by author

Spotlight

Advertisements