Issue 28, 2014
From the journal:

RSC Advances

The stereochemistry of two monoterpenoid diastereomers from Ferula dissecta†

Zhi-Qiang Wang,a   Chao Huang,a   Jian Huang,*a   Hong-Ying Han,b   Guo-Yu Li,b   Jin-Hui Wanga  and  Tie-Min Sun*a  

* Corresponding authors

a Key Laboratory of Structure-Based Drug Design and Discovery, Shenyang Pharmaceutical University, Ministry of Education, Shenyang 110016, PR China
E-mail: suntiemin@126.com
Fax: +86-24-23986398
Tel: +86-24-23986398

b School of Pharmacy, Shihezi University, Shihezi 832002, PR China

Abstract

Two diastereomeric monoterpene benzoates, tschimganin and iso-tschimganin, were isolated from the roots of Ferula dissecta. The absolute stereochemistry of the compounds was determined by chemical-related methods and ab initio calculations of electronic circular dichroism and 13C-NMR shifts. The antitumor activities of the diastereomers were also tested.

Graphical abstract: The stereochemistry of two monoterpenoid diastereomers from Ferula dissecta

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Article information

DOI
https://doi.org/10.1039/C4RA00547C
Article type
Communication
Submitted
19 Jan 2014
Accepted
07 Mar 2014
First published
12 Mar 2014

RSC Adv., 2014,4, 14373-14377

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The stereochemistry of two monoterpenoid diastereomers from Ferula dissecta

Z. Wang, C. Huang, J. Huang, H. Han, G. Li, J. Wang and T. Sun, RSC Adv., 2014, 4, 14373 DOI: 10.1039/C4RA00547C

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