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Issue 14, 2014
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Highly efficient [3 + 2] reaction of 3-vinylindoles with 3-indolylmethanols by Brønsted-acid catalysis

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Abstract

This paper describes a highly efficient [3 + 2] reaction between 3-vinylindoles and 3-indolylmethanols. Novel 2,3-bisindolylmethanes were prepared as single diastereoisomers in high yields with the promotion of 1 mol% 2-hydroxy-3,5-dinitrobenzoic acid.

Graphical abstract: Highly efficient [3 + 2] reaction of 3-vinylindoles with 3-indolylmethanols by Brønsted-acid catalysis

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Article information


Submitted
26 Nov 2013
Accepted
02 Jan 2014
First published
07 Jan 2014

RSC Adv., 2014,4, 6916-6919
Article type
Communication

Highly efficient [3 + 2] reaction of 3-vinylindoles with 3-indolylmethanols by Brønsted-acid catalysis

C. Zhang, L. Zhang, Y. Qiu, B. Xu, Y. Zong and Q. Guo, RSC Adv., 2014, 4, 6916
DOI: 10.1039/C3RA47056C

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