A zeolite supported Brønsted-acid catalyst system has been developed for the synthesis of novel N-substituted spiro[indole-pyridothiazine] analogs under ultrasonication in shorter reaction times with higher yields. The antiproliferative effects of the synthesized compounds were also tested against a wide range of tumor cell lines.
![Graphical abstract: Design, synthesis and biological evaluation of novel spiro[indole-pyridothiazine] analogs as antiproliferative agents](/en/Image/Get?imageInfo.ImageType=GA&imageInfo.ImageIdentifier.ManuscriptID=C3RA43908A&imageInfo.ImageIdentifier.Year=2014)
K. Arya, P. Tomar and J. Singh, RSC Adv., 2014, 4, 3060 DOI: 10.1039/C3RA43908A
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