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Issue 6, 2014
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Design, synthesis and biological evaluation of novel spiro[indole-pyridothiazine] analogs as antiproliferative agents

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Abstract

A zeolite supported Brønsted-acid catalyst system has been developed for the synthesis of novel N-substituted spiro[indole-pyridothiazine] analogs under ultrasonication in shorter reaction times with higher yields. The antiproliferative effects of the synthesized compounds were also tested against a wide range of tumor cell lines.

Graphical abstract: Design, synthesis and biological evaluation of novel spiro[indole-pyridothiazine] analogs as antiproliferative agents

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Publication details

The article was received on 25 Jul 2013, accepted on 29 Oct 2013 and first published on 31 Oct 2013


Article type: Communication
DOI: 10.1039/C3RA43908A
RSC Adv., 2014,4, 3060-3064

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    Design, synthesis and biological evaluation of novel spiro[indole-pyridothiazine] analogs as antiproliferative agents

    K. Arya, P. Tomar and J. Singh, RSC Adv., 2014, 4, 3060
    DOI: 10.1039/C3RA43908A

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