Jump to main content
Jump to site search

Issue 3, 2014
Previous Article Next Article

Recent advances in glycopolypeptide synthesis

Author affiliations

Abstract

Glycosylated peptides and proteins are ubiquitous in nature and display a wide range of biological functions including mediation of recognition events, protection from proteases, and lubrication in eyes and joints. Similarly, synthetic glycopolypeptides are also expected to show great potential as biomedical materials (e.g. scaffolds for tissue repair and drug carriers), as well as serve as valuable tools for probing carbohydrate–protein interactions. Although block copolypeptides and other complex polypeptide architectures have been known for some time, the synthesis of complex and well-defined glycopolypeptide materials, until recently, has been challenging. This article reviews the many advances and accomplishments made in the past few years toward development of strategies and methods for the preparation of synthetic glycopolypeptides via ring opening polymerization.

Graphical abstract: Recent advances in glycopolypeptide synthesis

Back to tab navigation

Article information


Submitted
09 Aug 2013
Accepted
19 Sep 2013
First published
01 Oct 2013

Polym. Chem., 2014,5, 671-682
Article type
Review Article

Recent advances in glycopolypeptide synthesis

J. R. Kramer and T. J. Deming, Polym. Chem., 2014, 5, 671 DOI: 10.1039/C3PY01081C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.


Social activity

Search articles by author

Spotlight

Advertisements