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Issue 28, 2014
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Impact of mono- and disubstitution on the colorimetric dynamic covalent switching chalcone/flavanone scaffold

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Abstract

The effect of aryl substitution on various aspects of the interconversion of ortho-hydroxychalcones and flavanones has been studied using multiple spectroscopic techniques. Derivatization of the core scaffold predictably alters the midpoint pH of this equilibration process suggesting its viability for application as a functional colorimetric molecular switch.

Graphical abstract: Impact of mono- and disubstitution on the colorimetric dynamic covalent switching chalcone/flavanone scaffold

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Publication details

The article was received on 20 Feb 2014, accepted on 28 Apr 2014 and first published on 06 May 2014


Article type: Paper
DOI: 10.1039/C4OB00398E
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Citation: Org. Biomol. Chem., 2014,12, 5108-5114
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    Impact of mono- and disubstitution on the colorimetric dynamic covalent switching chalcone/flavanone scaffold

    B. M. Muller, J. Mai, R. A. Yocum and M. J. Adler, Org. Biomol. Chem., 2014, 12, 5108
    DOI: 10.1039/C4OB00398E

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