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Issue 12, 2014
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Synthetic strategies toward hetidine and hetisine-type diterpenoid alkaloids

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Abstract

Within the diterpenoid alkaloid family of natural products, the hetidine and hetisine structural types have been the targets of a number of synthetic studies. Various strategies have been pursued to access the azacyclic moiety of these natural products as well as the characteristic [2.2.2] bicyclic structural motif. This perspective article examines the different disconnections and approaches that have been applied to the synthesis of these natural products to date.

Graphical abstract: Synthetic strategies toward hetidine and hetisine-type diterpenoid alkaloids

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Publication details

The article was received on 19 Dec 2013, accepted on 31 Jan 2014 and first published on 03 Feb 2014


Article type: Review Article
DOI: 10.1039/C3OB42541J
Citation: Org. Biomol. Chem., 2014,12, 1846-1860
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    Synthetic strategies toward hetidine and hetisine-type diterpenoid alkaloids

    A. M. Hamlin, J. K. Kisunzu and R. Sarpong, Org. Biomol. Chem., 2014, 12, 1846
    DOI: 10.1039/C3OB42541J

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