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Issue 14, 2014
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Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry

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Abstract

The use of state-of-the-art separation tools from the pharmaceutical industry for addressing intractable separation problems from academic synthetic chemistry is evaluated, showing fast and useful results for the resolution of complex mixtures, separation of closely related components, visualization of difficult to detect compounds and purification of synthetic intermediates. Some recommendations for potential near term deployment of separation tools within academia and the evolution of next generation separation technologies are discussed.

Graphical abstract: Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry

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Publication details

The article was received on 06 Nov 2013, accepted on 20 Feb 2014 and first published on 20 Feb 2014


Article type: Review Article
DOI: 10.1039/C3OB42195C
Citation: Org. Biomol. Chem., 2014,12, 2161-2166
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    Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry

    E. L. Regalado, M. C. Kozlowski, J. M. Curto, T. Ritter, M. G. Campbell, A. R. Mazzotti, B. C. Hamper, C. D. Spilling, M. P. Mannino, L. Wan, J. Yu, J. Liu and C. J. Welch, Org. Biomol. Chem., 2014, 12, 2161
    DOI: 10.1039/C3OB42195C

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