Highly efficient modular metal-free synthesis of 3-substituted 2-quinolones†
Abstract
A modular approach to 3-substituted 2-quinolones via a cascade annulation reaction between 4-nitroketones and hydrazines has been developed.
* Corresponding authors
a
Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., Stavropol 355009, Russian Federation
E-mail:
alexaks05@rambler.ru
Tel: +7 (918) 743 0255
b
Department of Chemistry, University of Kansas, 1251 Wescoe Hall Dr., Lawrence, KS 66045-7582, USA
E-mail:
mrubin@ku.edu
Fax: +1 (785) 864-5396
Tel: +1 (785) 864-5071
A modular approach to 3-substituted 2-quinolones via a cascade annulation reaction between 4-nitroketones and hydrazines has been developed.
A. V. Aksenov, A. N. Smirnov, N. A. Aksenov, I. V. Aksenova, A. S. Bijieva and M. Rubin, Org. Biomol. Chem., 2014, 12, 9786 DOI: 10.1039/C4OB02131B
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