Issue 43, 2014

Highly enantioselective phosphination and hydrophosphonylation of azomethine imines: using chiral squaramide as a hydrogen bonding organocatalyst

Abstract

Enantioselective phosphination and hydrophosphonylation reactions between azomethine imines and diarylphosphine oxides or dialkyl phosphites were respectively developed by the use of a chiral squaramide as the hydrogen bonding organocatalyst, which afforded two types of phosphorus containing product in high yields with good to excellent enantioselectivities.

Graphical abstract: Highly enantioselective phosphination and hydrophosphonylation of azomethine imines: using chiral squaramide as a hydrogen bonding organocatalyst

Supplementary files

Article information

Article type
Paper
Submitted
14 Jul 2014
Accepted
08 Sep 2014
First published
09 Sep 2014

Org. Biomol. Chem., 2014,12, 8656-8670

Highly enantioselective phosphination and hydrophosphonylation of azomethine imines: using chiral squaramide as a hydrogen bonding organocatalyst

L. Kong, N. Li, S. Zhang, X. Chen, M. Zhao, Y. Zhang and X. Wang, Org. Biomol. Chem., 2014, 12, 8656 DOI: 10.1039/C4OB01472C

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