A method for the selective transamidation of the 3-oxo sub-family of N-acyl homoserine lactones (3-oxo-AHLs) under physiologically relevant conditions has been developed. The reaction has the potential to serve as a strategy for selective knockdown of key autoinducers in a multicellular environment.
M. A. Bertucci, S. J. Lee and M. R. Gagné, Org. Biomol. Chem., 2014, 12, 7197 DOI: 10.1039/C4OB01156B
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