Issue 24, 2014
From the journal:

Organic & Biomolecular Chemistry

Copper-catalyzed bis-arylations of alkenes leading to oxindole derivatives†

Liangliang Shi,a   Yuyuan Wang,a   Haijun Yanga  and  Hua Fu*a  

* Corresponding authors

a Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, P. R. China
E-mail: fuhua@mail.tsinghua.edu.cn
Fax: (+86) 10-62781695

Abstract

A simple and practical copper-catalyzed approach to oxindole derivatives by copper-catalyzed bis-arylation of N-alkyl-N-phenylacrylamides with diaryliodonium triflates has been developed under mild conditions, and the method is of tolerance towards some functional groups in the substrates.

Graphical abstract: Copper-catalyzed bis-arylations of alkenes leading to oxindole derivatives

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Article information

DOI
https://doi.org/10.1039/C4OB00576G
Article type
Communication
Submitted
17 Mar 2014
Accepted
27 Mar 2014
First published
27 Mar 2014

Org. Biomol. Chem., 2014,12, 4070-4073

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Copper-catalyzed bis-arylations of alkenes leading to oxindole derivatives

L. Shi, Y. Wang, H. Yang and H. Fu, Org. Biomol. Chem., 2014, 12, 4070 DOI: 10.1039/C4OB00576G

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