Issue 24, 2014

A model study for tethering of (bio)active molecules to biomaterial surfaces through arginine

Abstract

A new approach for tethering of bioactive molecules via arginine is proposed and validated on collagen 2D matrices. The method involves the introduction of a methyl ketone on arginine side-chains, followed by reaction with model alkoxyamino derivatives.

Graphical abstract: A model study for tethering of (bio)active molecules to biomaterial surfaces through arginine

Supplementary files

Article information

Article type
Communication
Submitted
21 Jan 2014
Accepted
02 May 2014
First published
05 May 2014

Org. Biomol. Chem., 2014,12, 4089-4092

A model study for tethering of (bio)active molecules to biomaterial surfaces through arginine

F. Taraballi, L. Russo, C. Battocchio, G. Polzonetti, F. Nicotra and L. Cipolla, Org. Biomol. Chem., 2014, 12, 4089 DOI: 10.1039/C4OB00160E

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