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Issue 26, 2014
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A coumarin-quinolinium-based fluorescent probe for ratiometric sensing of sulfite in living cells

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Abstract

Based on a novel coumarin-quinolinium platform, probe 2 was rationally designed and synthesized as a novel ratiometric fluorescent sensor for sulfite anions. The probe exhibited a wide dynamic concentration range for sulfite anions in a PBS buffer (containing 1 mg mL−1 BSA). More importantly, the probe was suitable for ratiometric fluorescence imaging in living cells with high sensitivity, favorable selectivity, and minimal cytotoxicity.

Graphical abstract: A coumarin-quinolinium-based fluorescent probe for ratiometric sensing of sulfite in living cells

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Supplementary files

Article information


Submitted
18 Jan 2014
Accepted
02 May 2014
First published
02 May 2014

Org. Biomol. Chem., 2014,12, 4637-4643
Article type
Paper

A coumarin-quinolinium-based fluorescent probe for ratiometric sensing of sulfite in living cells

L. Tan, W. Lin, S. Zhu, L. Yuan and K. Zheng, Org. Biomol. Chem., 2014, 12, 4637
DOI: 10.1039/C4OB00132J

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