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Issue 13, 2014
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In vitro dosimetry of agglomerates

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Agglomeration of nanoparticles in biological fluids is a pervasive phenomenon that leads to difficulty in the interpretation of results from in vitro exposure, primarily due to differing particokinetics of agglomerates to nanoparticles. Therefore, well-defined small agglomerates were designed that possessed different particokinetic profiles, and their cellular uptake was compared to a computational model of dosimetry. The approach used here paves the way for a better understanding of the impact of agglomeration on the nanoparticle–cell interaction.

Graphical abstract: In vitro dosimetry of agglomerates

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The article was received on 23 Jan 2014, accepted on 17 Apr 2014 and first published on 21 Apr 2014

Article type: Paper
DOI: 10.1039/C4NR00460D
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Nanoscale, 2014,6, 7325-7331

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    In vitro dosimetry of agglomerates

    V. Hirsch, C. Kinnear, L. Rodriguez-Lorenzo, C. A. Monnier, B. Rothen-Rutishauser, S. Balog and A. Petri-Fink, Nanoscale, 2014, 6, 7325
    DOI: 10.1039/C4NR00460D

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