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Issue 24, 2014
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A new turn-on chemosensor for bio-thiols based on the nanoaggregates of a tetraphenylethene-coumarin fluorophore

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Abstract

In this work, a tetraphenylethene-coumarin hybrid fluorophore (TPE-Cou) that contains a Schiff base form is designed and synthesized. A combination of plentiful optical properties and chemical reactivity towards thiols allows TPE-Cou to work as an excellent turn-on probe of thiols with a wide linear range, revealing the great potential of this dye as a quantitative fluorescence indicator. By means of NMR and optical spectrum analyses, a mechanistic picture at the molecular level has been drawn to illustrate how this dye works as a bio-thiol-sensitive fluorescent probe.

Graphical abstract: A new turn-on chemosensor for bio-thiols based on the nanoaggregates of a tetraphenylethene-coumarin fluorophore

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Publication details

The article was received on 10 Aug 2014, accepted on 26 Oct 2014 and first published on 30 Oct 2014


Article type: Communication
DOI: 10.1039/C4NR04593A
Citation: Nanoscale, 2014,6, 14691-14696

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    A new turn-on chemosensor for bio-thiols based on the nanoaggregates of a tetraphenylethene-coumarin fluorophore

    X. Lou, Z. Zhao, Y. Hong, C. Dong, X. Min, Y. Zhuang, X. Xu, Y. Jia, F. Xia and B. Z. Tang, Nanoscale, 2014, 6, 14691
    DOI: 10.1039/C4NR04593A

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